EchoBridgeMD Pearl #16: Pitfalls of E-Point Septal Separation

An elevated E-point septal separation (EPSS) does not always indicate reduced left ventricular ejection fraction. EPSS may also be increased when anterior mitral valve leaflet excursion is mechanically restricted, such as in mitral stenosis or severe aortic regurgitation (see above).

Reference:

📖 Massie BM, Schiller NB, Ratshin RA, Parmley WW. Mitral E point septal separation: a reliable index of left ventricular performance in coronary artery disease. Am Heart J. 1977.

https://pubmed.ncbi.nlm.nih.gov/6869192/

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